Risk Factors Associated with Multiple End-Organ Damage in Idiopathic Thrombotic Thrombocytopenic Purpura (TTP) Patients
نویسندگان
چکیده
منابع مشابه
Plasmapheresis in thrombotic thrombocytopenic purpura (TTP)
A 70-year-old woman with thrombotic thrombocytopenic purpura (TTP) was treated with plasmapheresis using fresh frozen plasma as a fluid replacement. Complete recovery and lasting remission were observed. It appears that plasmapheresis combined with massive fresh frozen plasma can be an effective mode of treatment for patients who were, otherwise, refractory to conventional therapy.
متن کاملIpilimumab-induced thrombotic thrombocytopenic purpura (TTP)
BACKGROUND CTLA-4 (Cytotoxic T-lymphocyte-associated protein 4) was the first immune checkpoint receptor clinically targeted for use in cancer treatment. It is expressed exclusively on T-cells where its primary role is to regulate the amplitude of the early stages of T-cell activation.1 Ipilimumab, a CTLA-4 blocking antibody, has been widely used for the treatment of patients with high risk and...
متن کاملAutoimmune disorders in patients with idiopathic thrombotic thrombocytopenic purpura.
UNLABELLED 76 German patients suffering from thrombotic thrombocytopenic purpura (TTP) were interrogated about the prevalence of co-occurring autoimmune disorders. In order to analyze a possible association of TTP with the questioned diseases, a comparison of prevalence rates between the patient group and the general population has been made for each disease. RESULTS Compared to the estimated...
متن کاملCirculating immune complexes in thrombotic thrombocytopenic purpura (TTP)
We read with interest the article of Bukowski et al.1 about the treatment of plasmapheresis in TTP. These results suggested for these authors the existence of circulating immune complexes. Neame and Hirsh2 in their letter described two patients suffering from TTP in whom they were unable to detect circulating immune complexes with the Raji cell technique.3 Recently we studied a patient with a t...
متن کاملPregnancy-associated thrombotic thrombocytopenic purpura.
Thrombocytopenia during pregnancy is a common diagnostic and management problem. Several differential diagnosis must be considered including manifestations of thrombotic thrombocytopenic purpura (TTP). We report here on a case of a 21-year-old pregnant woman who presented initially severe thrombocytopenia (8 Gpt/l) in the 20(th)+1 week of gestation. The patient had an antibody against ADAMTS13,...
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ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v128.22.4928.4928